Polybamycin ointment is a topical antibiotic medication1. It contains the three antibiotics neomycin, polymyxin B, and bacitracin, and is used to reduce the risk of infections following minor skin injuries1. Polymyxin and bacitracin ointment is also used to treat skin infections caused by bacteria2. Bacitracin/polymycin ointment is used to treat eye infections3.